"irritating effect" is correct and usable in written English.
When used in a sentence, this phrase typically expresses the idea that an event or situation is causing frustration or annoyance for someone. For example, "The long wait in line had an irritating effect on my patience."
A cultish, worshipful atmosphere can prevail in Salzburg, to sometimes irritating effect.
(One figure that closely resembles Britten's "Young Person's Guide to the Orchestra" keeps returning to irritating effect).
Excess of chlorine produces characteristic unpleasant taste and odor and irritating effect on mucous membrane.
Vaccines are usually efficacious only with a certain degree of tissue injury induced by the irritating effect at the site of injection of the adjuvant.
Benefits: Simple method, Availability of inexpensive chemicals/cheaply available, Simple method, Availability of inexpensive chemicals/cheaply available, Limitations: Excess of chlorine produces characteristic unpleasant taste and odor and irritating effect on mucous membrane.
You may also want to re-consider your daily Clarisonic use -- cleansing devices trap bacteria in their bristles and can have the same irritating effect as an everyday scrub, Dr. Downie says.
Alcohol's irritating effects account for the heat.
Higher temperatures combined with sunlight provide the conditions that promote ozone, which has well-known irritating effects on the respiratory tract.
Deposition of thick mucus layer was found in the buccal cavity and gills of exposed fish probably to minimize the irritating effects of toxicant coming in close contact with body.
Measurements of pre- and post exposure eye redness, corneal thickness, tear film break-up time, conjunctival epithelial damage, blinking frequency, and subjective ratings on discomfort were used to evaluate the possible irritating effects of PGME.
In this study, for improving the activity of CAP and alleviating its irritating effects, a series of H2S-releasing CAPs were designed and synthesized by combining capsaicin and dihydro capsaicin with various hydrogen sulfide donors.
