Sentence examples for irreversibly inactive from inspiring English sources

In addition, these four mutants are temperature sensitive, in contrast to the couple of C-terminal mutants that are either low responsive or irreversibly inactive even at the permissive temperature.

The final state, however, is irreversibly inactive in substrate reduction.

An animal is considered dead when: 'respiration and blood circulation have ceased as the respiratory and circulatory centres in the medulla oblongata are irreversibly inactive.

Unlike other GPCRs (with the exception of a handful of protease-activated receptors), animal rhodopsins are covalently bound to an inverse agonist, 11- cis-retinal, such that the equilibrium is essentially irreversibly shifted to the inactive state until the photoisomerization of the chromophore occurs.

However, above a threshold value <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0007190.e062.PNG" class= inline-graphic"/> of <img src="http://journals.plos.org/plosone/article/asset?id=info:doi/10.1371/journal.pone.0007190.e063.PNG" class="inline-graphic"/> inactive neovascular cells switch irreversibly into active neovascular cells.

Static electricity can irreversibly damage these items.

NC9 binds to the active site of TG2 irreversibly [26] and therefore likely stabilizes the protein in an open, but inactive conformation [7].

Organophosphates irreversibly inhibit acetylcholine esterase, an enzyme that breaks down the neurotransmitter acetylcholine into inactive metabolites.

The co-crystal structure reveals that the inhibitor binds in the active-site cleft, irreversibly modifying the active-site cysteine; however, the catalytic histidine is still misaligned as seen in the native structure, suggesting that the inhibitor binds to an inactive form of the enzyme.

Both turbines operate irreversibly.

It is being irreversibly changed".