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The phrase "irreversibly changed" is correct and usable in written English.
You could use it to describe a situation in which a certain event has had permanent consequences. For example, "The automobile industry was irreversibly changed by the introduction of new technologies."
Exact(34)
It is being irreversibly changed".
The student movement, she said, had irreversibly changed Chile.
The strength of the story, though, is that Mr Shah, too, is irreversibly changed.
TI OK, let's posit that music's value really has irreversibly changed.
When Amma finally figures out the problem, it is already too late and her world is irreversibly changed.
The Canal Hotel bombing, as it became known, irreversibly changed the security situation in which humanitarian aid workers operate.
Similar(26)
Barnosky was the lead author of a 2012 paper that warned of a global tipping point at which Earth's systems would irreversibly change as a result of changing climate.
It doesn't take a very long time to irreversibly change the planet.
Massive proliferations of scyphozoan jellyfish considerably affect human industries and irreversibly change food webs.
The heat causes the proteins in each cell to irreversibly change, like an egg white as it boils.
This hydrated form irreversibly changes to a dehydrated variety at relatively low temperatures (60° C) or upon being exposed to conditions of low relative humidity.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com