Cameron's insistence that the settlement terms must be immediately seen to be legally watertight and irreversible suffered a setback when the head of the European parliament said he could not guarantee that.
The Tiananmen Square massacre in 1989 scared away a lot of investors, but Cheng figured it was just a setback on an irreversible journey toward economic liberalization.
Their stance is irreversible and will represent a significant setback for José Mourinho, who had been under the impression a deal to take him to Stamford Bridge was only a matter of time.
I learned from our experience in Northern Ireland that ending violence and making peace irreversible requires patience, taking risks, suffering setbacks and a constant commitment.
In a statement on Tuesday, Mr. Bloomberg called the ruling "a temporary setback" and referred to "the irreversible health impacts of obesity and Type 2 diabetes — both of which are disproportionately linked to sugary drink consumption".
'We cannot deny that, despite some recent setbacks, the trend towards universal abolition is irreversible.'.
"If we think that when this protocol was adopted in 1989, only half of the countries that today voted in favor of the resolution were abolitionist, we cannot deny that, despite some recent setbacks, the trend towards universal abolition is irreversible," Maria Donatelli, executive director of the World Coalition Against the Death Penalty, told VICE News.
Over the temporary setbacks, the clamour for reform or democracy is irreversible," Anwar said.
Russian food import ban is a major setback for globalisation - At one point globalisation seemed inevitable and irreversible, says the Washington Post's Anne Applebaum.
Irreversible brain damage is irreversible.
