The last one I did burned an irreversible pattern on to my monitor.
The first is that to have a 50/50 chance of avoiding tipping our eco-system into an irreversible pattern of rising temperatures we can only risk putting about 700 gigatonnes more carbon dioxide into the atmosphere.
They provide experimental evidence that in a physiological process of cell fate induction, Xenopus oocyte maturation, a bistable signalling system of a MAPK cascade converts a transient stimulus into a reliable, self-sustaining, effectively irreversible pattern of protein activities.
All patients with SMAP showed an irreversible pattern of platelet microaggregates by a low dose of ADP.
Gray-matter reduction of NAA with the basal ganglia and cerebellum is consistent with the concept that sustained childhood lead exposure produces an irreversible pattern of neuronal dysfunction.
Furthermore, the patients with SMAP showed an irreversible pattern of platelet microaggregation by ADP, and the degree of SMAP correlated with the enhanced expression of active GP IIb/IIIa and P-selectin, indicating that SMAP is pathophysiologically active.
Regardless of the status of albuminuria, the platelet microaggregates in all patients with SMAP showed the irreversible pattern after stimulation by a low dose of ADP, and those in the patients without SMAP were reversible.
Gray-matter NAA reductions associated with increasing childhood blood lead levels suggest that sustained childhood lead exposure produces an irreversible pattern of neuronal dysfunction, whereas associated white-matter choline declines indicate a permanent alteration to myelin architecture.
The diabetic patients with SMAP showed an abnormal and irreversible pattern of platelet microaggregation, even after stimulation by a low dose of ADP (Fig. 1 C), whereas a normal reversible pattern was observed in patients without SMAP and in all healthy volunteers (Fig. 1 D).
However, as most of morphogenetic events of animals are irreversible, the patterns that we can observe have been completed and are fixed.
