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Repeated exposure to hyperglycemia can lead to endothelial pathology that may become irreversible over time [ 32].
PTHMs and DNA methylation can become irreversible over time, explaining the long-lasting detrimental effects of metabolic memory, which induce T2DM vascular complications even after improvement of glycemic control.
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Sulfur severely poisons the Au/TiO2 catalyst, which is irreversible over time-on-stream under high pressure (21 bar) WGS conditions.
Because this approach most commonly makes use of an irreversible reaction, fluorescent signal accumulates over time, and reversible sensing is not possible.
Furthermore, they reported that loosely bound proteins will over time evolve to form an irreversible bound protein.
Users should implement QA systems to check the quality of irreversible compression over time.
This pathway can lead the progression from endothelial activation, already reversible alteration, toward endothelial damage that may become irreversible alteration over time.
"People change over time.
We found that treatment with PAO led to a loss of cell motility and uropod formation that was irreversible over the time scale of our experiments (Figure 3A, B).
While these effects were irreversible over observation times of several hours, they were not accompanied by cell lysis.
Hunter syndrome is a progressive disease that affects multiple systems and results in irreversible organ damage over time.
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