Sentence examples for irreversible disruption from inspiring English sources

Finally, brain death results in an irreversible disruption of consciousness.

This causes an irreversible disruption of ER homeostasis [9].

This cleavage results in an irreversible disruption of vimentin filaments that precedes the dramatic reorganization of the cytoskeleton that typifies apoptotic cell death.

Repeated or prolonged depolarization as a result of such disrupted ion homeostasis can eventually lead to excitotoxicity; in this case, excitotoxicity is likely to occur in the CA3 hippocampal region, resulting in a massive intracellular calcium influx and leading to the activation of Ca2+ dependent phospholipases, the irreversible disruption of the membrane, and cellular lysis [22].

In P. berghei it has been shown that by infection of mice with >100000 mutant sporozoites intravenously 'break-through' parasites are observed that give rise to blood stage infection, despite irreversible disruption of the p36p gene by double cross-over recombination.

A microbubble, if driven by intense ultrasound, will suffer irreversible disruption.

Above a certain PEF intensity, reversible pore formation become irreversible wall/membrane disruption (Zderic et al. 2013).

Such an interaction may lead to irreversible bilayer disruption after membrane binding.

In newborn mice where brain development is in a critical period, exposure to persistent organochlorines, such as PCBs, has been shown to cause severe, sometimes irreversible, brain disruption (Eriksson 1997; Eriksson et al. 2002).

At high strain, a major fraction of the energy loss is attributed to irreversible, longer ranged disruption of the PS domains leading to permanent morphological change and permanent set.

Immediately after mechanical trauma due to impact or penetration, neurons can die by necrosis caused by membrane disruption, irreversible metabolic disturbances and/or excitotoxicity [ 14].