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Irrespective of the expression pattern in normal tissues, we found 77 genes that were over expressed (in relation to normal breast) in primary breast tumors.
Furthermore, we find that these TAD boundaries are present irrespective of the expression and looping of genes located between them.
Surprisingly, addition of SB203580 completely abolished the BMP-2 induced cell migration irrespective of the expression of the phospho-mimetic mutant (Fig. 7B).
In a mouse model, an increased expression of NKG2D after DNA vaccination was correlated with an improved NK and CD8 T cell response to tumor cells, irrespective of the expression of NKG2D ligands [35], [36].
First, K48-mediated polyubiquitination of α-tubulin occurred irrespective of the expression of MGRN1 or MGRN1ΔR.
Irrespective of the expression of FAK or FRNK, the level of total Akt remained unchanged.
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Tumors were considered positive for both, membranous and cytoplasmic staining by using the above mentioned criteria, irrespective of whether the expression of the antibodies was localized in the same cell or in different groups of tumor cells (Fig. 3).
Irrespective to the expression levels of DRs, a molecular interaction between ganglioside GM3, abundant in lymphoid cells, and DR4 was detected.
Likewise, the effect of high HER4 (irrespective of the HER3 expression) in combination with high expression of HER1 or HER2 was analysed.
A gene with relatively even distribution across tissues will have an elevated E (will be broadly expressed), irrespective of the total expression level.
The expression of Hsp70 and Hsp27 were unchanged at the ages tested irrespective of the transgene expression or age of mice.
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