Irrespective of genotype, the ARR was in favor of DrotAA (estimated weighted mortality: DrotAA 25.1%, nonDrotAA 30.5%) (P = 0.006, Additional file 1: Supplement Table 21).
In general, neither BW nor MW were related to either AD or SB; LS was negatively correlated (p < 0.01) with both BW and WW, irrespective of genotype.
Inflammation drives the proliferation of AIEC and dysbiosis in the ileum, irrespective of genotype.
Circulatory diseases and cancers accounted for the highest numbers of prevalent diseases at death, irrespective of genotype.
However, sperm from the Msh2 line exhibited low percentages of sperm with DNA damage or abnormal chromatin irrespective of genotype.
While BSE failed to transmit, vCJD transmitted infection to all three lines though with variable efficiency, strengthening the concern of an iatrogenic risk irrespective of genotype.
As shown in Figure 4B, λ5 mRNA was not detected in splenic B cells, irrespective of genotype (See also Supplemental Figure S1A).
Irrespective of genotype, novel target pictures elicited increased activation of an extensive ventral visual network, including the fusiform and parahippocampal gyrus when compared to familiar pictures (Figure 2A).
Pachytene spermatocytes from the Msh2 line did not show elevated levels of damage in terms of γH2AX immunostaining irrespective of genotype which was expected as mismatches do not lead to DNA breaks but could however cause replication errors and mutations.
In the no handling groups, there were significantly higher levels of activity in the playground groups compared to the home cage groups, irrespective of genotype and sex (F 1,143) = 125.438, p<0.001; Figure 7A).
