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Helium, prized for its unique combination of physically desirable qualities, is irreplaceable for many purposes.
During Godard's 1968 speaking tour of American universities, one student said he was "as irreplaceable, for us, as Bob Dylan".
"Mark is not irreplaceable for this mission," Professor Logsdon said, "and naming a backup is the prudent thing for NASA to do.
What a tribute to my palpable impact and how right I was for my times that I have been irreplaceable for 16 seasons.
I suspect that Steinbrenner will prove irreplaceable for those millions of fans who have relished hating him and his vaunted team for the last 34 years.
Although Mr. Flowerdew acknowledged that most hobbyists would do fine without peat, he maintained that it was irreplaceable for cultivating certain hard-to-grow plants and for getting seeds to sprout.
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"But what would we do without you, Auntie?" Don't let this young woman's sweet voice deceive you, Auntie Mei warned herself: you're not irreplaceable — not for her, not for Baby, not for anyone.
"The site has already suffered four years of conflict, it suffered from looting and represents an irreplaceable treasure for the Syrian people and for the world," Ms Bokova said.
BLSOM will become a novel, irreplaceable strategy for function prediction of proteins for which only ambiguous or no prediction was obtained with sequence homology searches.
At the 2007 Black Entertainment Television (BET) Awards, Beyoncé won Video of the Year Award for "Irreplaceable", an award for which "Beautiful Liar" was also nominated.
Mr. Met has for decades been the lovable and irreplaceable symbol for the organization, but this year, the bullpen will have a mascot of its own, known affectionately as Stosh.
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