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Whereas Zasp localizes correctly at the Z-band in ΔC3GMS mutants, the Z-band itself is irregular, raising the possibility that the integrin mislocalization observed in ΔC3GMS mutant animals may partially be the result of defective anchorage of actin filaments to the Z bands.
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The isolate produced irregular, raised, grey white colonies with light yellow substrate mycelium on ISP2 agar surface.
Borders: Benign lesions are usually regular and flush with the skin while melanomas may have irregular and/or raised borders.
Some nodules, due to their confluence tendency and irregular appearance, raise the problem of differential diagnosis with neoplastic disorders [ 10, 34, 35].
Slit-lamp examination of the right eye showed a 12 mm white-yellowish central corneal epithelial defect with irregular and raised edges, along with intense hyperemia of the conjunctiva, photophobia and pain.
The auditor discovered "irregular transactions that raised concerns of fraud," the F.H.A. said.
A more irregular texture should raise the suspicion of superinfection or steatonecrosis (Fig. 10b).
The flow of contrast material flow into the diverticulum, together with irregular borders, should raise suspicion of chronic inflammatory or neoplastic changes [2].
This research joins a host of other studies that document the ways working irregular shifts harms health, including raising the risk of diabetes, obesity, some cancers, workplace injury and heart disease.
MBCT can depict areas of irregular luminal narrowing and shouldering of the margins, raising the suspicion of an underlying malignancy (Fig. 3a, b).
The fraction of the irregular-shaped particles in the final latex increased as the duration of raising the temperature was set longer, while the irregularity developed from dumbbell to more progressive shapes.
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