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This is in contrast to our study where such areas of mottled appearance of hypo- and hyper-reflectance on OCTA en face and structural en face images were due to irregular loss of signal transmission and not due to focal choriocapillaris ischemia or hypoperfusion as suggested in the previous studies.
An irregular loss of photoreceptor nuclei has also been found, which seems inversely correlated with the age of the subjects and with the lipofuscin levels on the adjacent RPE [ 21– 26].
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The treated cells showed a decrease in size and irregular shape; loss of cytoplasm and light staining; plasmolysis; and appearance of bubbles [Fig. 5a (iii)].
2, 13 Keratinocytes become irregular with loss of polarity and disordered melanocytes.
Irregular rainfall and loss of topsoil means that the land produces less than before.
The pancreas shows diffuse or focal enlargement with irregular narrowing and loss of the pancreatic cleft and smooth rim (capsule-like rim).
The bacteria when incubated with the AuNPs showed distorted morphology, disintegration of the outer membrane resulting in irregular outline, and loss of integrity of cell shape and size (Fig. 6p).
At a later stage, fibrosis leads to luminal irregular narrowing, and loss of the structural support of the cartilage leads to tracheobronchomalacia, which is seen as tracheobronchial collapse and air trapping on the expiratory CT scan [11, 24].
When the weight ratio of chitosan/Fe was from 2/3 to 1, the CS-coated Fe3O4 NPs became morphologically rough and irregular and exhibited loss of structural cohesion (Figure 5d,e,f).
Corneal ectatic diseases (such as keratoconus and post-LASIK corneal ectasia) lead to corneal biomechanical instability, resulting in myopia, irregular astigmatism and loss of best spectacle corrected visual acuity.
Adenomas with carcinoma in situ exhibited marked glandular complexity, including areas with a cribriform configuration and marked cytological atypia, characterized by large irregular nuclei and loss of nuclear polarity.
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