Sentence examples for irregular alterations from inspiring English sources

We then measured PDCD4 mRNA levels in the same CRC tissue pairs and detected irregular alterations in PDCD4 mRNA levels between the tumor and paired non-tumor tissues (Fig. 1C).

Glutamine, fructose-6-phosphate amidotransferase, is the rate-limiting step of the hexosamine biosynthesis pathway, which activates as an alternative pathway to glycolysis for the utilization of hyperglycemia-induced overproduction of fructose-6-phosphate, resulting in excess of N-acetylglucosamine and irregular alteration of gene expression of plasminogen activator inhibitor-1 and TGF- β.

Moreover, overexposure to CFCs and related halogenated hydrocarbons can cause arterial hypertension, myocardial infarction and temporary alteration of the electrical activity of the heart (atrial and ventricular cardiac arrhythmias) manifested with palpitations, irregular pulse or even inadequate circulation.

In this analysis, high running loads in sports such as marathons, ultramarathons, triathlons, and long high-intensity bike rides can cause negative effects such as acute inflammations; in the long term, these activities may lead to chronic inflammation, irregular fibrosis formation, alterations in the size of the cardiac chambers, and atrial fibrillation [54].

Yeasts treated with 2.5 μg/ml of subfraction F2.4 showed more-drastic alterations with irregular buds emerging from the lateral of the mother cells instead of from the usual terminal, complete loss of the normal cellular ovular shape, cell wall detachment (arrows), membranous structures (arrowheads) and extracted cytoplasm suggesting cell death (Figs. 2E-F).

Indeed, various atypical size and cell shape alterations, for example, irregular, swollen, oval-shaped, and defective cells were obviously noticeable, especially in the treated MRSA (Figure 3C), while these aberrations were not observed in the untreated control cells (Figure 4C).

These gait alterations increase on irregular surfaces [ 3].

On imaging, these lesions may show imaging features suggestive of a brain tumor or abscess displaying solitary or multiple focal areas of signal alteration with an irregular peripheral enhancement and a mild to moderate mass effect on adjacent brain structures.

A further structural alteration was that the irregular rose window of the facade was replaced by a more regular round-arched window like the smaller ones flanking it.

Lateral plain radiograph shows marked morphological alteration of the heel with irregular lytic areas and concomitant PF thickening (double-head arrow) due to spreading of the infection (a).

As exposure continues, the respiration cycle can become irregular, largely through decreased input as well as alterations in the endogenous pacemaker.