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The Nobel assembly said the pair had used "tenacity" to challenge prevailing theories about stomach disease, making an "irrefutable case" that this bacterium caused more than 90% of duodenal ulcers and up to 80% of gastric ulcers.
In its citation, the Nobel committee from the Karolinska Institute in Stockholm said that Marshall and Warren "made an irrefutable case that the bacterium Helicobacter pylori" causes ulcers and other diseases.
The New York Times review was written by Al Gore: "… in her timely, meticulously researched and well-written book, Kolbert combines scientific analysis and personal narratives to explain it to us … She makes an irrefutable case that what we are doing to cause a sixth mass extinction is clearly wrong".
When evidence became irrefutable that Kevadon caused horrendous birth defects, the company quietly withdrew its application.
Indeed, after decades of such studies of smoking behavior, the correlation between smoking and bad outcomes like cancer, heart disease, stroke, emphysema and other ills became so apparent as to consider it irrefutable that smoking causes many diseases.
On the one hand, the craving for secrecy, order, and acts of executive will that brook no opposition; on the other hand, the need for simplicity, the love of vicarious battles and intoxicating emotions, and a cause as irrefutable as a local team to lead the cheering for.
One fact is irrefutable, autism is not caused by vaccinations.
''As the authors of many of these reports, we encourage you to understand that despite the clinical and objective language we have used in our professional roles – these reports document intense suffering experienced by families, children and individuals and are irrefutable evidence of the harm caused by offshore detention," she said.
Educationally I think the case is irrefutable.
The evidence in this case is irrefutable.
What they discovered, and described in their classic book, "When Prophecy Fails," is that the irrefutable failure of a prophecy does not cause true believers — people who have committed themselves to a belief both emotionally and by their life choices — to reconsider.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com