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In addition, flow cytometry analysis revealed that I seeds were more effective in stimulating ROS generation than X-ray irradiation at the same doses.
The SFs of cells exposed to I seed irradiation were significantly lower than that of cells exposed to X-ray irradiation at the same doses, both in U251 and U87 cells.
Evaluation of RBE (ERBE) was expressed as the relative amount of gamma-H2AX protein following high-LET irradiation divided by the same parameter post low-LET irradiation at the same time point.
The results of our study indicate that the number of TUNEL-positive cells was significantly increased with I seed irradiation as compared with X-ray irradiation at the same doses.
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The design of the high flux test module developed at the Forschungszentrum Karslruhe (FZK) allows for maximizing the space available in the high flux neutron field for material irradiation, while at the same time allowing precise adherence of the irradiation temperature of the specimen stacks.
Therefore, GdSL could deliver drugs to specific sites by ultrasound irradiation and, at the same time, allow MR imaging due to enhanced T1 relaxivity.
In fact, salivary cells are still capable of amylase secretion shortly after irradiation while at the same time water secretion seems specifically and severely impaired.
Surprisingly, the PB signatures of partial body irradiation demonstrated low accuracy in predicting the radiation status of other mice irradiated at the same dose level to other parts of the body (Figure 2).
Secondly, nanocarrier drug composites have the dual functions: they act as drug carriers to deliver GA into cancer cells and function as TiO2 Ws under UV irradiation for PDT at the same time.
The histological appearance of the irradiated testes at 14 days after irradiation was the same as those at 7 days after irradiation, and spermatogenesis was restored at 28 days (1 month) after irradiation.
ALDH3A1 irradiated for 15 min at 1 mg/ml displayed a loss of approximately 50% of its specific activity but irradiation for the same time at 0.01 mg/ml caused a greater than 90% loss.
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