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This change is not observed either immediately after irradiation or in cytoplasm irradiated cells.
While the clonogenic capacity of control non-irradiated cells decreased with the number of replating, the clonogenic capacity of cells 7 days after 6 Gy irradiation increased, suggesting that irradiated cells have a higher clonogenic capacity than non-irradiated cells.
In comparison to non-irradiated cells (∼500 μm3), the nuclear volume of irradiated cells was increased 8-fold (to ∼4000 μm3) at day 7 post irradiation.
By 24 hr after irradiation with 8 Gy, there was a 26% reduction in the number of irradiated cells compared with sham-irradiated cells (p < .01).01
Irradiated cells and not-irradiated cells were separately cultured in tissue culture flasks.
Irradiated cells were washed twice with LPM medium.
Similar(6)
By 24 hours post-irradiation, cell cycle distribution resembled non-irradiated cells (Figure 3A).
The viability of UV-irradiated cells was calculated as fraction of the control values.
The ratio was calculated for 40 control and 40 centrosome-irradiated cells.
Our findings showed that caffeine pretreatment of UV-irradiated cells, prevents P-TEFb LC dissociation.
Non-irradiated cells were used as control.
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