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The equilibrium spectrum [9], [19] for the steady-state pupil constriction (n = 4 subjects) is based on measures obtained in each subject at each of the 11 different pre-exposition wavelengths and corrected according to the complete irradiance dose response curves of the 2 subjects recorded in the initial experiments to obtain the half saturation values.
With both procedures we calculated a nonlinear correlation of the vitamin D weighted irradiance dose and the serum level of 25(OH)D3.
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Growth experiments in the laboratory with daily irradiance doses up to 21.6 mol photons m−2 per day showed increasing growth rates with increasing irradiances.
The cornea was then exposed to ultraviolet radiant energy from a solid-state UV lamp source (light-emitting diode (LED)) at a wavelength of 365 370 nm (in the UV-A spectral band) at an irradiance ("exposure dose rate") of 30 mW/cm2 for 3 min to achieve a total radiant exposure ("total dose") of 5.4 J/cm2.
These data were related to the prevailing irradiances and doses of PAR and UVR, measured in high resolution by a spectroradiometer, within the particular water depths.
The corneas were then irradiated with UVA for 30 minutes (irradiance 3 mW/cm; dose 5.4 J/cm) using a 370 nm UVA double-diode light source.
This was followed by irradiation for a period of 2 minutes 40 seconds (irradiance 45 mW/cm; dose 7.2 J/cm).
The extent of Se effect was dependent on the culture treatment, i.e. Se dose, irradiance intensity and time of exposure.
Differences in irradiance, accumulated PDT dose and tumor vascularity may affect observed blood flow patterns [ 36].
Before treatment, an intended 3.0 mW/cm2 of surface irradiance (5.4 J/cm2 surface dose) was calibrated using a UV light meter at a working distance of 5 cm.
Laser irradiation was performed three times (once a day for three consecutive days) with a 660 nm 50 mW CW laser, beam spot size 2 mm, irradiance 2.5 W/cm2 and irradiation times of 60s (dose 150 J/cm) and 420s (dose 1050 J/cm) respectively.
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