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The underlying mechanisms whereby iron loading of hepatocytes leads to the pathology of the liver are not understood.
Iron loading of hepatocytes resulted in decreased E-cadherin promoter activity and subsequently decreased E-cadherin mRNA and protein expression.
Results and conclusions: The levels of iron loading of macrophages in vitro or in vivo affect the growth of M. avium.
Iron phosphide catalysts supported on silica with an iron loading of 15 wt% were synthesized and studied in the hydrodeoxygenation (HDO) of phenol.
The Fe2O3/SiO2 material prepared with sodium silicate and a theoretical iron loading of 20 wt.% achieved the highest resistance to the iron leaching.
Double-walled carbon nanotubes (DWCNTs) were prepared by methane decomposition on Fe/Al/Mg/O catalysts with a fixed iron loading of 1.5%.
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The aim of the present study was to characterize the effects of iron loading on proteins critically involved with apoptotic processes in the hippocampal formation.
The iron-treated group that received CBD in adulthood had also significantly higher Cytochrome c levels when compared to the control group (p = 0.001), suggesting that CBD was not able to reverse the effects of iron loading on Cytochrome c protein levels.
We propose that anti-proliferative or other toxic effects of iron loading on normal cells, rather than mitogenic effects on pre-neoplastic cells, explain tumor promotion in the T51B cell model.
The same conclusions were drawn via the reduction of water proton relaxation times T∗2, resulting from the different iron load of labeled cells using a 1.5 T clinical MR imager.
At the end of the study, 21 weeks after stem cell implantation, no trace of the implanted, β-galactosidase positive cells was observed on histological sections, and only traces of the iron load of the 10% labeled cells was found at the injection site (data not shown).
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