Sentence examples for ipsc in from inspiring English sources

This includes the hitherto inability to produce large cell masses of iPSC in defined culture media.

This study was designed to test the effects of induced pluripotent stem cell (iPSC) in the treatment of chronic myocardial ischemia.

This information can be used to improve our choice of reprogramming approach (SCNT versus iPSC) in future endeavors, as well as identifying groups of supportive (but not essential) genes that might be used to augment efficiency in the reprogramming process.

This was the case for the IVF procedure and recombinant DNA techniques in the 1970s, the mammalian cloning technique (i.e., the birth of the Dolly sheep) in the 1990s, the generation of inducible pluripotent stem cells (iPSC) in the 2000s and mitochondrial DNA (mtDNA) transfer in embryos in 2013, to name just a few in recent memory.

In general, compared to the allograft, the immunogenicity of autologous iPSC derivatives is much weaker, supporting not only by the high teratoma formation rate by B6 iPSCs than allogeneic 129 ES cells in the B6 mice, but also the fact that T cells are only locally but not ubiquitously infiltrated into the teratomas formed by iPSC in B6 mice.

This is immensely critical for the employment of iPSC in multi-lineage differentiation protocols[15], [16].

The iPSC-iN method might thus be the currently most efficient way to differentiate human iPSCs to functional neurons.

Recently, a new approach has been developed to combine direct conversion with ESC and iPSC methods, termed ESC-iN and iPSC-iN [ 120].

In particular, aberrant DNA methylation states found in iPSCs are a major concern when using iPSCs in a clinical setting.

Next, we investigated the potency of the iPSCs in directed cell differentiations.

MEFs could be successfully converted into mouse induced pluripotent stem cells (iPSCs) in 3D collagen scaffolds.