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Called the Firefly, this digital sensor cleaner uses ionization technology to remove the static charge of the dust so it just falls off.
Ionization technology ESI was showed to be more convenient for polar lipids and some other less-polar lipids [190], [191].
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The ability of both techniques to be coupled with mass spectrometry (MS) and the different ionization technologies developed including electrospray ionization (ESI), matrix-assisted laser desorption/ionization (MALDI), and atmospheric pressure chemical ionization (APCI) has vastly improved their sensitivity.
Electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI) are two soft ionization technologies which are widely applied to the analysis of glycoproteins and glycans.
The integration of soft ionization technologies and ultrahigh resolution FTICR mass spectrometry (Fourier transform ion-cyclotron MS) has enabled the examination of molecules, directly from mixtures, with ultrahigh mass resolution and sub-ppm mass accuracy.
Tags were analyzed in a single quadrupole mass spectrometer by using positive-mode atmospheric-pressure chemical ionization (Agilent Technologies, Wilmington, DE, USA) (7 ).
PCR coupled to electrospray ionization mass spectrometry technology (PCR/ESI-TOF-MS) (PLEX-ID system, Abbott Ibis Biosciences) was developed to characterize microbial pathogens.
All measurements were done using Agilent LC MS/MS system that consisted of LC (Agilent HPLC 1200) coupled to MS/MS detector (6410 QqQ MS) through an electrospray ionization source (Agilent Technologies, USA) [17].
The resulting methyl esters of 3-hydroxybutyrate were characterized by gas chromatography as described previously (Brandl et al. 1988; Timm and Steinbüchel 1990) by using an Agilent 6850 GC (Agilent Technologies, Waldbronn, Germany) equipped with a BP21 capillary column (50 m by 0.22 mm; film thickness, 250 nm; SGE, Darmstadt, Germany) and a flame ionization detector (Agilent Technologies).
GC analysis was performed directly from this solution using a 6890N GC with a split/splitless injector, a 7683B automatic liquid sampler, and flame ionization detection (Agilent Technologies, Palo Alto, CA).
Peptides were separated using a 40 min 5 45% FB linear gradient (FA = 0.1% formic acid, FB = CH3CN, 0.1% formic acid) at a flow rate of 0.4 µL min−1 and analyzed online by a 6330 Ion Trap Mass Spectrometer with a Nano-Electrospray (nanoESI) ionization source (Agilent Technologies).
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