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Usually, the ion-substituted CaPO4 are of a non-stoichiometric nature with just a partial ionic substitution and there are too many of them to be described here.
This phenomenon is termed ionic substitution, or solid solution.
The second major type of ionic substitution is interstitial solid solution, or interstitial substitution.
The temperature at which crystals grow also plays a significant role in determining the extent of ionic substitution.
An additional factor affecting ionic substitution is the maintenance of a balance between the positive and negative charges in the structure.
As a result, ionic substitution that could not have occurred in crystals grown at low temperatures may be present in those grown at higher ones.
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If such a variety is caused by ionic substitutions that are minor but consistent, they are called polytypoids.
Among ionic substitutions, those between ions of distinctly different sizes most significantly affect geometric configurations of silicate layers.
Unlike pyrophyllite and talc, the 2 1 silicate layers of smectite have a slight negative charge owing to ionic substitutions in the octahedral and tetrahedral sheets.
By this distortion mechanism, tetrahedral and octahedral sheets of a wide range of compositions resulting from ionic substitutions can link together and maintain silicate layers.
Similarly, ionic substitutions in hydroxyapatite or in tricalcium phosphate create lattice defects that modify the sintering rate.
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