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A modified ion funnel is described.
An experimental and theoretical investigation of the ion funnel is presented.
The FTICR instrument was equipped initially with ESI source and ion funnel optics.
The enhanced performance compared with previous ion funnel designs optimized for pressures of <5 torr was achieved by reducing the ion funnel capacitance and increasing the RF drive frequency (1.7 MHz) and amplitude (100 170 V peak-to-peak).
We also report an alternative treatment of the ion funnel operation based on the effective potential approximation.
These are used to deduce a greater understanding of the operation of the ion funnel and the sensitivity improvements.
This represents an important undertaking in the characterization studies of ion funnel technology for use in PTR-MS.
The analytical relationships derived are used to generalize the results of computer simulations and develop an optimized ion funnel design.
Here we summarize the results of the simulations for several ion funnel configurations and their comparison with experimental measurements.
Ion funnel 1 RF: 200 Vpp; ion funnel 2 RF: 200 vpp; hexapole RF: 200 Vpp; quadruple ion energy: 5 ev; quadrupole low mass: 55 m/z; collision energy: 5.0 ev; collision RF: ramped from 800 to 1,500 Vpp; transfer time: from 100too 155 μs; pre-pulse storage time: 5 μs.
A radio frequency ion funnel reaction chamber is applied for use with a proton transfer reaction ion trap mass spectrometer (PIT-MS).
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