Sentence examples for involving significant changes from inspiring English sources

Marketing innovation is the implementation of a new marketing method involving significant changes in product design or packaging, product placement, product promotion or pricing [17, 18].

However, during fast metabolic transitions involving significant changes in the pyruvate concentration, primarily resulting from major changes in glycolytic rate, the LDH isoenzyme pattern may well play an important role in the compounded metabolic response to altered energy metabolism.

Individuals living with diabetes often suffer from lifelong self-management regimens, involving significant changes in lifestyle such as diet, weight control, exercise, and other health-promoting behaviors, as well as adherence to complex medication regimens.

"It would involve significant changes to how central government operates".

The reorganization, which involves significant changes for every part of Disney except for the movie division, sets up a structure for Disney to absorb the Fox businesses.

The transformation of Poland's economic system in the 1990s as a result of transition from a centrally planned economy to a market-based system involves significant changes in the regulatory context and in accounting practice and education.

The court's conservatives could say that they've already found that for a quid pro quo to exist, it has to involve significant changes to policy that are unquestionably done in exchange for a gift or contribution, so there's really no reason to limit contributions, because most of them won't involve that kind of exchange.

"Without question we're in a period of transition that involves significant changes in the way we do business," Wetherell says.

It should also be stressed that the implementation of activation strategies in OECD countries has generally involved significant changes in labour market policy institutions, legislation, and management principles, as well as in the design of specific programmes.

The obtained results indicate that estimation of the position at a sufficient accuracy for most of the location-based services does not have to involve significant changes in the terminals and in the network infrastructure.

Alvarez-Curto et al [50] found that this adaptation involved significant changes in the expression pattern of the car1 gene, coding for the cAMP receptor involved in chemotaxis.