Your English writing platform
Discover LudwigExact(1)
The standard triage of drug discovery involves potency testing in vitro (MIC studies), followed by efficacy testing in animal models after ensuring adequate plasma levels that merit the test of the hypothesis.
Similar(59)
I present a kinematic method involving potency rate, that is fault area times slip rate.
Venom attacks can range in severity from a simple localized inflammation of the skin to almost immediate death, depending on the animal involved and the potency and mode of action of its venom.
Our theoretical results indicated that halogen bond interactions could be involved with differential potency of these compounds and provide a new starting point to design novel pyrazolo[1,5-c]quinazolines as new anti-Alzheimer agents.
In opposite to HFD-fed mice, young hyperphagic mice show likely enhanced potency involved in the lipogenesis processes.
The model predicts that the equivalent P2X1 receptor residues K70, R292 and K309 that are involved in ATP potency also mediate antagonist action.
In the second study, using a similar method but involving only sexual potency and survival, men without prostate cancer were willing to trade 10% of a 5-year survival (about 6 months) to maintain sexual potency (Singer et al, 1991).
This shows that key residues involved in ATP potency do not have an effect on suramin sensitivity, and indicate there is not significant overlap in the particular residues involved in suramin and ATP binding.
Thus, in light of the broad medicinal evidence of the importance of OX receptors as potential drug targets, there is a need for the exploration of the key structural features of OX receptors involved in agonist potency, efficacy, and selectivity.
The estrogenic potency of a compound involves its binding affinity, bioavailability in serum, and persistence in the environment.
In doing so, the papers in this issue ask critical questions about the nature of these novel forms of foresight practice and investigate the trade-offs and potencies involved in the workings of mediated scenarios.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com