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The mechanism of protection probably involves multiple effects including metabolic effects, antioxidant mechanisms, activation of KATP channels, as well as inhibition of inflammatory cell activation.
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Desalination of sea water involving multiple-effect evaporator (MEE) is commonly used in industry, especially with the introduction of the low temperature MEE.
These results showed that face adaptation involves multiple complex effects.
Quantitative trait locus (QTL) theory predicts that genetic influence on complex traits involves multiple genes of small effect size.
This is a well-known idea and when genes function primarily through a complex mechanism that involves multiple genes, the joint effect (behavior) of those genes' variants is referred to as a gene-gene interaction (or epistasis) [ 8- 10], though biological interaction and statistical interaction are often confused [ 11].
Antiangiogenic therapies have been transferred from preclinical to clinical application in recent years (Ellis and Hicklin, 2008; Kerbel, 2008), but their clinical efficacy is relatively modest and a therapeutic benefit of VEGF-targeted therapy probably involves multiple mechanisms, beside its antiangiogenic effect.
All of this is consistent, therefore, with the idea that the underlying genetic causation is polygenic and involves multiple alleles of relatively individually small effect, across many different genes.
Susceptibility/resistance to Chagas disease involves multiple genetic variants functioning jointly, each with small or moderate effects.
Bullrun involves multiple sources, all of which are extremely sensitive".
Rarely, it involves multiple nerve territories.
Its breakdown involves multiple biochemical reactions.
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