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Perhaps the most exciting use of AI in forecasting involves its ability to continually monitor aspects such as market shifts, natural disasters, competitive responses, and political landscapes.
The essence of bupivacaine-induced cardiac toxicity involves its ability to block myocardial cell ion channels.
Diclofenac sodium is a nonsteroidal anti-inflammatory agent whose mechanism of action in the treatment of actinic keratoses involves its ability to inhibit cyclooxygenase (COX -2.
These data indicate that EEP may protect macrophages from ox-LDL-induced apoptosis and the mechanism at least partially involves its ability to suppress the CD36-mediated ox-LDL intake and subsequent activation of ER stress-CHOP signalling pathway.
The best-known mechanism of BDE47 toxicity involves its ability to impair the homeostasis and function of thyroid hormone (TH) in animals because of its structural similarity to THs such as triiodothyronine (T3) and thyroxine (T4).
14 The mechanism of action of fluorouracil involves its ability to interfere with the synthesis of nucleic acids through its metabolite, 5-fluorode-oxyuridylic acid, which inhibits thymidylate synthase.
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These findings suggest that the protective effects of CAPE against CCl4-induced acute liver injury may involve its ability to block CYP2El-mediated CCl4 bioactivation and to protect against Fas/FasL-mediated apoptosis.
The majority of the gankyrin research has involved its ability to stimulate proteasome-dependent degradation of pRB and p53, and its role in pRB phosphorylation [27], [32].
Taken together, these results suggest that P. aeruginosa DinB contributes to H2O2-induced mutagenesis by one or more mechanisms that are functionally distinct from that involving its ability to catalyze error-prone bypass of 8-oxo-dG (see Discussion).
The harmful side effects of chloroquine in the late phase appear to involve its ability to induce apoptosis and to inhibit autophagy.
Functional consequences of the truncated receptor protein could involve its ability to interact with SSTR5 or SSTR2 leading to non-functional heterodimers.
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