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TPM sample preparation involves assembly of the relevant DNA tethers and their associated reporter beads.
MVB formation involves assembly of the multiprotein complexes known as ESCRT on the late endosomal membrane.
Formation of the mammalian sperm head involves assembly and different polarization of two novel spermiogenesis-specific LINC complexes.
Cell migration involves assembly and disassembly of FAs and is stimulated extracellularly and initiated by intracellular signaling proteins located in FAs [ 5, 6].
Similar issues exist in biology, for example, protein synthesis that involves assembly of different amino acids is vulnerable to mistakes by erroneous incorporation of a wrong amino acid.
From the mechanistic point of view, it was shown that activation of survival pathways by TRAIL involves assembly of a secondary signaling complex that retains the DISC components FADD and caspase-8, and recruits RIP1, TRAF2, TRADD and NEMO/IKK.
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The model is validated using case studies involving assembly of automotive engine accessories.
"We can do some very precise localization of the different pieces with sub-millimeter precision, so we can also navigate technicians through a protocol involving assembly of very small components," said Amich.
Upstream initiator Caspases become activated through protein interactions involving assembly of multi-protein complexes (reviewed in [2], [3]), which are often difficult to reconstitute in vitro.
Nuclear remodeling during sperm head formation requires an elaborate cooperation of different cellular mechanisms that involve assembly of sperm-specific cytoskeletal structures, nuclear movement and chromatin compaction [34] [38].
Alternatively, the growth inhibitory effects of AGN 194310 may result from direct pharmacological effects involving assembly of RAR complexes containing corepresser molecules.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com