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Calibration involves additional assumptions about the instrument, the calibrating apparatus, the quantity being measured and the properties of measurement standards (Rothbart and Slayden 1994; Franklin 1997; Baird 2004: Ch. 4; Soler et al. 2011).
While molecular evolution is undoubtedly an interesting avenue of research, incorporating process-models into phylogenetic hypothesis testing, involves additional assumptions which are always likely to be arbitrary, over simplified, or even just plain wrong [33], [39], [40].
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By definition, however, parametric kernel methods always involve additional assumptions about the form of the distributions governing the data that nonparametric methods do not make.
Additional corrections to this model involve additional assumptions and may still be misleading [21], and no precise temporal hypotheses are being evaluated with these data, therefore no additional testing or adjustment of rates was done.
Second, since none of the studies used to obtain effectiveness data included QALYs as an outcome measure, it was felt that incorporating QALYs would involve additional assumptions about the relationship between patient health states (relapse/no relapse) and QALYS and would not necessarily result in a significant relative difference in the outcomes.
We need additional assumptions on F near infinity.
If depends on, we have to require additional assumptions.
Otherwise, they require additional assumptions which can introduce error.
Indeed, the addition of telonemids, centrohelids, and Rhizaria involves additional photosynthesis and/or plastid loss events to explain the observed distribution of photosynthesis under the assumption that the common ancestor of all chromalveolates was photosynthetic.
Furthermore, other conventional methods involves additional problems.
Costing based on health states has been used previously 15 and involves some additional assumptions, including that health states are the main driver of costs and that the previously identified costs for the health states generalize to this patient population.
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