The p53 response varies across cell and tissue types, and involves a spectrum from transient cell cycle arrest to senescence and apoptosis (Stiewe, 2007).
Acupuncture is a complex intervention that always involves a spectrum of treatment factors (pathologic-specific effects) and associated effects (placebo, non-specific, context effects), which makes it extremely difficult to fully unravel the inner mystery of this biological phenomenon [ 10].
The design and manufacturing of a chemical product and its process involve a spectrum of physical and chemical phenomena, over characteristic scales that cover many orders of magnitude, from molecular design at 0.1 nm to global warming at 104 km.
Productive pursuit of this topic has inescapably involved a spectrum of political, cultural, personal, and interpersonal factors that are normally not encountered in more conventional scientific scholarship, but have both enriched and complicated the enterprise in many ways.
Systems of education must discuss and understand their own raison d'être from a sophisticated philosophical and educational perspective, also taking thoroughly into account a future perspective, involving a spectrum of potential futures.
To the best of our knowledge, this is the first case report involving a spectrum of abnormalities associated with poor prognosis in AML-M4 [E0].
The number of studies is rapidly expanding, and involve a spectrum of agents including COX2 inhibitors (Harris et al, 2000), HER1 and HER2 kinase inhibitors (Kurokawa and Arteaga, 2001), farnesyl transferase inhibitors (Johnston et al, 2003) and mTOR inhibitors (Mita et al, 2003).
These behavioral tasks were selected as they assess locomotive, balance, anxiety-related and social contextual behaviors in Mecp2-deficient mice that have relevance to co-morbidities seen clinically in Rett syndrome patients (17), and involve a spectrum of different neural circuitries.
His firm but loving approach to Apollo (and, then, to other horses he's invited to train) is an utterly absorbing display of a talent that involves a vast spectrum of concentration, empathy, courage, self-control, and dexterity, along with a fund of experience and knowledge to draw upon.
This involves a wide spectrum of approaches, from simple passive walking theories to large-scale computational models integrating the nervous, muscular and skeletal systems.
In an era of next generation sequencing and synthetic cells, these concerns have far from evaporated, while the field of Science Studies addressing them has significantly broadened, so that it now involves a broad spectrum of disciplines besides philosophy proper.
