"As you accumulate more and more evidence that Avandia has this problem, and it involves a very serious consequence, namely heart attack and death, it puts a lot of pressure on the F.D.A. to do more".
First, there is a large uncertainty on the outcome of the selection and drift processes involved, a natural consequence of the coalescence process that directly affects disequilibrium, and hence predictive ability.
It involves running a consequence model around a hundred times and using the results to construct a statistical emulator, which is essentially a sophisticated curve fit to the data.
(All I'll say is that it involves a pig.) The consequences, though, are proportionate to what you might expect from a summer blockbuster action movie.
Health economic analysis will initially involve a cost-consequences analysis of all the costs and outcomes collected [ 35].
Elastin degradation has been investigated by several groups [ 14, 41- 45] conducting analyses of the cleavage pattern and of proteases involved as a consequence of inflammation and macrophage activity.
Particularly when a biological invasion involves an ecosystem engineer, the consequences for an invaded ecosystem can be catastrophic [ 3].
We report that one unanticipated consequence of economic downturns involves an increased risk of male CD.
This model for gelatin gels considers appropriately the interplay between the networks involving: (a) viscoelastic relaxation as a consequence of an imposed mechanical history, (b) average degree of physical cross-links in the partially generated permanent network acting in the short-term mechanical response.
But in a case involving a public agency with consequences that affect the public interest, there has to be some kind of acknowledgment that certain things did occur, she added.
A level 4 accident is defined as having local consequences involving a release of radioactive materials exceeding 0.1% of core inventory with a high probability of significant public exposure and at least one death from radiation.
