Sentence examples for involvement of this modification from inspiring English sources
Interestingly, Nsa1 is strongly poly-ubiquitinated in vivo (D. Kressler and E. Hurt unpublished data), which hints at a possible involvement of this modification in substrate recognition or processing.
Detection of stronger signal in the P fractions indicates the prevalence of ubiquitinated species in them and also strengthens the argument for the involvement of this modification in the polymerization of α-tubulin.
The strong stimulatory effect of HDAC-inhibitors on SM production in several fungi (see above) suggested a significant involvement of this histone modification in SM cluster regulation.
We found that BACE1 is abnormally modified, with higher levels of bisecting GlcNAc being observed in AD patients, suggesting the pathological involvement of this sugar modification on BACE1 during AD development.
Several serine-type endopeptidases or associated proteins were present within this group and lacking from the others, suggesting potential involvement of protein modification in adaption to the human GI tract environment.
The involvement of functional modification of Hd1 by day length is further supported by the direct manipulation of OsGI expression and the resulting change in Hd1 and Hd3a expression levels [19].
To examine the involvement of metabolic modification to the enhancement of cytotoxicity by retinoids, we investigated the activation of AMPK in cells after treatment.
The shared function of the Ccr4-Not and the Bur1/2 kinase complexes in H3K4 tri-methylation [7] prompted us to test involvement of this kinase complex in post-translational modification of the Ccr4-Not complex.
In the absence of a preexisting template that would assist the change, the involvement of a covalent modification, transient or irreversible and affecting either all or a minor subset of molecules, as a trigger was postulated and never discarded [9], [11].
The determination that inhibition of O-GlcNacase prevented the increase in axonal branches induced by forskolin suggests regulatory involvement of O-GlcNac modification on proteins involved in cAMP signaling.
Our study identified the involvement of repressive histone modification in p53-mediated CD133 suppression.
