Sentence examples for involvement of the cluster from inspiring English sources

Involvement of the cluster in chromomycin A3 biosynthesis was demonstrated by disrupting the cmmWI gene encoding a polyketide reductase involved in side chain reduction.

Biochemical analysis of the NcpA1 and NcpB1 adenylation domains coupled with the recent characterization of the (2S,4S -5-hydroxyleucine dehydrogenase NcpD, which is involved in the biosynthesis of the nonproteinogenic amino acid residue l-4-methylproline from l-leucine, support the involvement of this cluster in nostocyclopeptide biosynthesis.

The involvement of this cluster in neural development was further supported by its significant enrichment in postsynaptic density, the Alzheimer's disease-presenilin pathway and the brain (Benjamini corrected P = 0.003, 0.001, and 0.05 respectively, fig. 6 A).

Functional enrichment suggested strong involvement of this cluster in the Notch signaling pathway (Benjamini corrected P = 4.01 × 10−), which plays a major role in neurogenesis and neuronal differentiation (fig. 6 A).

The involvement of the miR-17-92 miR-17-92 miR-17-92he funcluster role of p38α was examediatingng p38α/miR-17-92 concomithet knockdown cells (SH3/miR).

In these respects, the involvement of the 11p15.5 cluster in the physiopathology of PE fits well with the recent observation that the invalidation of p57/kip2, another gene of this cluster results in "preeclampsia-like" symptoms in mice [ 48].

Involvement of the ste gene cluster in exopolysaccharide biosynthesis was confirmed by disrupting the priming glycosyltransferase gene in Streptomyces sp. 139 to generate non-exopolysaccharide-producing mutants.

These data supported the involvement of the alkB gene cluster in the n-alkane degradation in the R7 strain.

These data supported the involvement of the alkB gene cluster in the n-alkane degradation in R7 strain.

Therefore, our study could be considered an independent replication of the involvement of the MSA4A gene cluster in AD.

We validated the possible involvement of the miR-23a cluster in modulating TGF-β activity to facilitate the Zeb1-mediated EMT process.