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Electromagnetic solutions offer acceptable accuracy without direct involvement of radiation.
However, the mechanism mediating this increased risk and the potential involvement of radiation exposure have yet to be elucidated.
As for the mutation of Sfpi1, however, there is no direct data about the involvement of radiation in its induction.
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Compelling evidence for the involvement of UVB radiation comes from the prevalence of transitions at dipyrimidine sites that are generally regarded as signature UVB mutations.
We also wished to establish whether abnormalities of visual function are related to brain MRI findings and more specifically not only to the involvement of optic radiations and occipital cortex but also to changes in the thalami, that are often affected in infants with PVL.
This indicates that either the involvement of whole brain radiation somehow magnifies the toxicity of TMZ and HCQ or that the 6-wk continuous daily dosing of TMZ as opposed to the intermittent dosing of the dose-intense regimen studied in this trial, was the reason why myelosuppression was observed with the former and not the latter approach to TMZ dosing.
There has been recent interest in whole-body MRI to demonstrate osseous, soft tissue and nodal involvement, without the use of radiation[ 5 9].
Involvement of the optic radiations is rare.
These results suggested the possible involvement of P21 in radiation-induced senescence and decreased sprouting, migration and proliferation.
Involvement of Lck in radiation-induced proliferation and resistance in glioma patients has also been reported [ 31].
The distribution pattern of immunohistochemical staining for TNFα in irradiated colon demonstrates a direct involvement of TNFα in radiation-induced mucosal shedding.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com