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The involvement of area V4 in intermediate form processing is also supported by compromised pattern discrimination in a patient with a brain lesion in this area [4].
In our study, the greater activation of BA19 for dynamic than for static actions indicates involvement of area V5/MT, which has been shown to respond not only to real motion [20] but also to implicit [21], [22] and illusory [23], [24] motion.
For instance, a study of visual motion showed that individual monkeys with, on average, more sensitive and consistent neurons in the midtemporal cortical area (MT) were better able to discriminate changes in the direction of motion [6], strengthening the case for the involvement of area MT in motion discrimination.
This strengthens the model of a direct involvement of AreA in the activation of terR expression.
In contrast, our results suggest involvement of area 3b in processing Aδ-mediated nociceptive information that is elicited by high-intensity electric stimulation.
Apart from grasping studies, the involvement of area aIPS has also been demonstrated in reaching tasks, both with and without vision of the hand (Desmurget et al. 2001; Filimon et al. 2007, 2009; Taubert et al. 2010).
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However, no information about temporal involvement of areas was provided in that study.
Finally, duration distortions induced by violations of progressive number sequences implicate the involvement of high-level predictability, suggesting the involvement of areas higher than primary visual cortex.
The involvement of areas associated with anticipating action consequences was indexed by activation clusters in inferior parietal cortex/supramarginal gyrus and ventral premotor areas (see Table 1; Figure S1).
To investigate the involvement of areas in conformity with, or independence of the expert, we probed for brain regions showing differential responses when following vs. ignoring the expert's advice.
It might be associated with the absence of cardiac-gated T1-weighted sequence applied in our study, as with this technique, MRI was considered being helpful in reducing the cardiac motion artifact that significantly influenced the evaluation of tumor involvement of areas of mediastinum [ 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com