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However, inhibitors specific to both β and γ-secretases inhibited the expression of smaller SMP30 forms suggesting their possible involvement in the processing of SMP30. Figure 1 shows the expression of SMP30 in HEK-293A cells (A) and in C3A liver cells (B).
The results revealed a network of temporal regions, covering anterior STG and MTG bilaterally and posterior STG and MTG in the LH, and suggesting bilateral temporal involvement in the processing of grammatically complex sequences.
Consistent with this position, there is good evidence of NAc involvement in the processing of hippocampal-dependent spatial information (e.g., Annett, McGregor, & Robbins, 1989; Ferretti et al., 2005; Seamans & Phillips, 1994).
PTPH1 expression in the granule cells seems to indicate a potential involvement in the processing of afferent information to the purkinje cells, since it is known that afferents fibers to the cerebellar cortex will project in part through the granule cell layer.
We have previously shown that coilin has RNase activity in vitro and can cleave the precursor transcripts of both U2 snRNA and hTERC (Broome et al., 2013; Broome and Hebert, 2012; Broome and Hebert, 2013), which supports the idea of coilin involvement in the processing of these RNAs.
A third set of regions, within the right GP (Fig. 2b), the left inferior parietal lobe (extending into the occipito-parietal junction; Fig. 2d), and the left precuneus (Fig. 2e) showed selective involvement in the processing of unexpected familiarity when compared to expected familiarity, but no modulation for novelty.
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Our results reinforce the hypothesis of an early (around 100 ms) modulation of brain activity by not consciously perceived facial expressions [34], and the involvement, in this processing, of a large distributed neural network, including amygdala and frontal regions [6], [18].
The involvement of Ca2+ in the processing of the precursor, but not in the actual peptidase activity, suggests that in pro-TPPI, different residues may be involved that cleave off the pro-segment.
Here we apply massively parallel Illumina sequencing to probe the involvement of miRNAs in the processing of song experience in the zebra finch auditory forebrain.
Working in fibroblasts, which do express endogenous PMP22 (Manfioletti et al., 1990), but lack PMP22-binding Schwann cell proteins, such as protein zero, allowed us to evaluate the involvement of HSP70 in the processing of this aggregation-prone molecule.
The mechanism whereby Rnase10 confers adhesiveness onto spermatozoa in the proximal epididymis has yet to be uncovered, although the loss of the mature form of ADAM3 and ADAM6 from spermatozoa suggests Rnase10 involvement in the processing and stabilization of these proteins within the sperm plasmalemma.
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