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The finding of upregulation of TNF-α expression in this case brought us to further research on its involvement in the induction of CXCR4 expression by H. pylori.
Second, numerous investigations into autoimmune disease have provided evidence of NF-κB involvement in the induction of inflammatory cytokines and other mediators of inflammation that drive the pathology.
Because the NuRD complex is a high confidence interactor of Oct4 and a key regulator of developmental cell state transitions, we have investigated its involvement in the induction of pluripotency.
While its involvement in the induction of apoptosis in NS0 cultures has recently been disputed [ 15], the tight regulation of Gadd153 by culture-related stresses makes it a promising indicator of culture health.
Our interest is consequently drawn to its involvement in the induction of CXCR4 expression by H. pylori, a potent inducer of TNF-α, which is known to upregulate a series of cytokines, chemokines, adhesion molecules and growth factors in cancers.
Analysis of these smRNAs levels in leaves of high altitude landraces, and their levels after UV-B exposure are currently under study to understand their possible involvement in the induction of P1.
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As p38/cPLA2 is involved in the regulation of nucleated cell apoptosis and the possible involvement of p38/cPLA2 in the induction of platelet apoptotic events is not known, we compared the mechanism of p38/cPLA2-mediated signaling induced by platelet agonists and ABT-737.
The direct evidence for the involvement of CYP1A1 in the induction of cardiotoxicity by Pb2+ was evidenced by the ability of AhR antagonist, resveratrol, to significantly inhibit the Pb2+-modulated effect on β-MHC and α-MHC mRNAs.
Finally, we tested the involvement of Smac/DIABLO in the induction of apoptosis by hUCBSC.
To assess the involvement of P53 in the induction of apoptosis, ewsr1a or ewsr1b MO were co-injected along with a p53 MO.
This was consistent with an involvement of JunB in the induction of one chain but not of the other, the latter serving as a negative control in the above experiments.
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