Sentence examples for involvement in the expression from inspiring English sources
Therefore, even though Rel2 may be involved in the defense against malaria infection, its involvement in the expression pattern of many antimicrobial genes may greatly reduce the possibility of this gene specifically exhibiting an evolutionary response to Plasmodium.
First, we explored the requirement of TLRs in NF-κB induction while the above-mentioned report investigated TLR involvement in the expression of various inflammatory molecules (e.g., TNFα, MCP-1, IL-12).
To provide further evidence of the role of ELT-2 in innate immunity, we studied its involvement in the expression of the gene clec-67, which encodes a C-type lectin.
Surprisingly, however, few studies have investigated their involvement in the expression of impulsive behavior.
Our previous observations showed that NEU3 was upregulated in various human cancers and its involvement in the expression of malignant properties differed depending on the cancer types.
The range in phenotypes caused by disruption of GATA4 function is partly due to its involvement in the expression of sarcomeric genes including Myh6, Myl1, and Tnni3 (Di Lisi et al., 1998; McGrew et al., 1996; Molkentin et al., 1994).
The tumour suppressor role of CTCF was suspected because of its involvement in regulating the expression of some genes that are directly implicated in cancer (i.e., MYC, IGF2, p53, P27, p19/ARF and BRCA1) (Bell and Felsenfeld, 2000; Klenova et al, 2002; Qi et al, 2003), its cell growth inhibitory effect and its genetic mapping to 16q22.1.
Given ZEB1's involvement in mediating the expression of early adipogenic commitment factors, we next tested whether ZEB1 also regulates adipogenesis in uncommitted precursors such as the C3H10T1/2 MSCs.
In the Shaker K+ channel these sidechain interactions were originally revealed by their involvement in the surface expression of channels presumably because they stabilize the structure of the K+ channel during the maturation of the protein and transit to the surface [4], [18].
Thus one might speculate about an involvement in the decreased expression of THADA in dedifferentiated thyroid cells.
The aim of this study was to evaluate human leukocyte antigen (HLA) involvement in the disease expression and poor prognostic clinical features (pulmonary fibrosis and pulmonary arterial hypertension) in patients diagnosed with systemic sclerosis (SSc) in a multiethnic population.
