Sentence examples for involvement in the complement from inspiring English sources
On the other hand, as shown here and elsewhere [17], [18], [19], [45] the classical pathway has a limited involvement in the complement activation by T. cruzi in non-immune serum, suggesting that natural antibodies would have a limited capacity to recognize T. cruzi and activate the complement system.
These results are surprising because in human RA the involvement of the complement network in the development of arthritis has generally been assumed to reflect the classical pathway of activation involving the recognition of ICs by C1.
Collectively, our results and the abovementioned de novo mutations studies warrant further investigation to probe the involvement of the complement pathway in ASD.
The present study provides important data suggesting for the first time the involvement of the complement system in the genetic susceptibility to epileptic seizures and to epilepsy.
The involvement of the complement system in various diseases has stirred the development of several assays to evaluate deficiencies in the three activation pathways.
The involvement of the complement system in AMI has been concluded from both animal models and human studies where the affected areas in the heart stained positive for several complement components, including C1q, mannose-binding lectin, C3 and C5b-9.
Involvement of the complement system in the development of mouse models of arthritis caused by autoantibodies has been demonstrated using C5-deficient mice.
The presence of a similar consequence for C3 and C5 knockdown in cancer cells pointed to the involvement of the complement activation pathway, rather than C3 alone, in promoting tumor growth.
Recent studies provide evidence of the involvement of the complement system alterations in schizophrenia-associated immune system abnormalities including autoimmunity and inflammation [ 13- 17].
In addition, new results from our laboratory are presented regarding the involvement of the complement factor, mannose-binding lectin, in septic shock patients.
There is growing evidence for an important role of the complement system in CNS development and functioning and for the involvement of the complement system and particularly of C3 dysregulation, in the epilepsies – including the MTLE.
