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Automated, intelligent vehicle control systems have gained importance in recent years, as they have the potential to increase road safety by removing human involvement in driving.
It will also carry a Cosworth Formula 1 engine, although this will have no direct involvement in driving wheels as it does on a racing car.
Again, its involvement in driving the chromosome 5 loss remains to be established.
The major sources of intracellular ROS are mitochondria and NADPH oxidase and we analysed their possible involvement in driving ESOM-mediated ROS accumulation.
Having uncovered a role for PVRL4 in enabling epithelial cells to escape growth restriction associated with the lack of proper matrix anchorage, we next sought to test its involvement in driving the tumorigenic properties of breast cancer cells.
DOI: http://dx.doi.org/10.7554/eLife.00358.018 We have shown that PVRL4-driven anchorage-independent growth is dependent on its involvement in driving cell-to-cell attachment, which raises an interesting possibility that in the context of the altered matrix environment that tumor cells encounter, certain types of intercellular interactions function to enable anchorage-independent survival.
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Due to the lack of active involvement in the driving situation and due to monotonous driving environments drivers with automation may be prone to become fatigued faster than manual drivers (e.g. Schömig et al., 2015).
Thus, these findings from both human cancer patients and animal models of cancer cachexia strongly support the involvement of FoxO in driving the muscle atrophy process.
Our demonstration of a critical involvement of CGRP in driving the sensitization of the joint in experimental models of OA, along with published clinical evidence of an association between joint expression of CGRP and symptomatic OA in humans emphasizes the relevance of CGRP to OA pain.
Here we compare the involvement of IL-1 in driving innate immune responses in multiple tissues including the brain.
However, the ability of NHU-ECmut cells to display consistently higher growth rates irrespective of extracellular calcium levels (Figure 4B) was suggestive of potential involvement of additional signalling pathways in driving cell proliferation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com