As several studies have made clear, it involves substantial costs ('cost discovery') (Hausmann and Rodrik 2003).
It may first consider retrofitting the buildings of the most vulnerable construction type, for example, the miscellaneous and brick-wood buildings; then retrofitting composite masonry, which will involve substantial costs, can be considered.
However, extra-group matings also involve substantial costs as they occur during violent encounters that sometimes result in injury and death.
Administration by infusion using a central vein catheter involves substantial costs, whereas replacing it with oral therapy combined with drugs administered intravenously results in savings in health resources for the hospital which translates into a reduction in the time that the medical staff spend administering therapy and more efficient use of the day hospital.
Such restoration work involves substantial cost, and it is important to know if the benefits generated from "living streams" are greater than restoration costs.
However, PET imaging is not suited to screening test of general population because PET examination involves substantial cost.
While non-contract physicians to some extent enlarge the consumer choice for publicly funded outpatient care, private treatments usually also involve substantial cost sharing.
However, the traditional cost-effectiveness analysis of diagnostic tests has involved collecting additional data on alternative treatments that could involve substantial cost and sometimes might be difficult to collect (46, 47).
It also represents a cost saving for society, since these biologicals often involve substantial financial costs.
External stockpiles and waste dumps occupy considerable space as well as involve substantial transportation costs to move materials from open pits to stockpiles and then move them back to the pit for rehabilitation after the end of exploitation.
