Exact(1)
More ancient branches seem to have involved the highest values of ω, which is consistent with the view that the early stages of duplication and diversification among mammalian β-defensin paralogs involved strong selection.
Similar(59)
By contrast, the evolution of the PpDAM genes has involved strong purifying selection, suggesting important functions in peach trees that rely upon the retention of specific sequences.
Another possibility involves strong truncating selection with gradually increasing selective pressure – in this case all haplotypes that can withstand a given concentration will have equal fitness at that concentration regardless of their ability to withstand higher concentrations.
The domestic dog is a rich resource for mapping the genetic components of phenotypic variation due to its unique population history involving strong artificial selection.
Cultivation of organisms for production purposes such as agriculture, livestock, forestry, and aquaculture inevitably involves strong artificial selection, both intentional and unintentional, on a variety of morphological, physiological, behavioral, and life-history traits (Ledig 1992; Mignon-Grasteau et al. 2005; Hutchings and Fraser 2008).
It seems likely that evolution in biofilms typically occurs under conditions contrary to what is typically assumed in standard population genetics theory (e.g. strong selection and weak mutation) and rather involves strong mutational mechanisms typical in bacteria under stress [ 41] coupled with weak selection (see also [ 26]).
Domestication is an excellent model for studies of adaptation because it involves recent and strong selection on a few, identified traits [ 1 5].
A simple hypothesis for helping to explain this pattern involves a history of strong selection for genetically based, environmentally induced growth allocation patterns (e.g. relative allocation to brain, vascular system, insulin system function, immune function, etc).
In other words, salmon domestication may not involve classical selective sweeps with strong selection on loci with large effects driving beneficial alleles to fixation, but instead subtle shifts in allele frequencies in QTLs underlying adaptation to the hatchery environment.
Granted, there is a strong selection bias involved (people are more likely to add the application if they hate the new Facebook), but there's no denying that a substantial number of Facebook users are not pleased with their new homepage.
In fact, a functional enrichment analysis shows that strong selection candidates involved with signal transduction (p = 5.1 × 10−4) and neuronal activities (p = 0.04).
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