Sentence examples for involved significant changes in from inspiring English sources
It should also be stressed that the implementation of activation strategies in OECD countries has generally involved significant changes in labour market policy institutions, legislation, and management principles, as well as in the design of specific programmes.
Alvarez-Curto et al [50] found that this adaptation involved significant changes in the expression pattern of the car1 gene, coding for the cAMP receptor involved in chemotaxis.
Early IVD degeneration involved significant changes in numerous pathways, including Wnt/β-catenin signaling.
The transformation of Poland's economic system in the 1990s as a result of transition from a centrally planned economy to a market-based system involves significant changes in the regulatory context and in accounting practice and education.
Marketing innovation is the implementation of a new marketing method involving significant changes in product design or packaging, product placement, product promotion or pricing [17, 18].
"Without question we're in a period of transition that involves significant changes in the way we do business," Wetherell says.
The obtained results indicate that estimation of the position at a sufficient accuracy for most of the location-based services does not have to involve significant changes in the terminals and in the network infrastructure.
This might involve significant changes in the physiology and metabolism of individuals under selection [ 25].
As shown previously, cyst cell development involves significant changes in cell membrane and cell wall composition that presumably provides extreme desiccation resistance.
Early (subclinical) degeneration of the IVD, which is characterized by changes in the NP cell population, involves significant changes in the expression of genes involved in canonical Wnt signaling, ultimately leading to downregulation of this pathway.
However, during fast metabolic transitions involving significant changes in the pyruvate concentration, primarily resulting from major changes in glycolytic rate, the LDH isoenzyme pattern may well play an important role in the compounded metabolic response to altered energy metabolism.
