Panels of top ranked gene candidates, major gene hubs and commonly involved pathways in both the smoking and cancer related network were identified.
While GWAS have been successful in reporting numerous genetic associations and highlighting involved pathways relevant to reproductive aging, for ovarian disorders, such as premature ovarian insufficiency and polycystic ovary syndrome, research has lagged behind due to insufficient study sample size.
During the metastatic process of melanoma, involved pathways are mainly composed of the following: MAPK signaling pathway, cell cycle, p53 signaling pathway, apoptosis, and melanogenesis.
The presented model can be used for integration of even more models in the context of the apoptosis/survival switch to finally improve the analysis of all involved pathways and the understanding of the holistic network.
In the present study we showed correlations between ACE and sex hormones, satiety hormones, insulin related hormones, LEP and other blood metabolic proteins, suggesting its broad range of substrates and involved pathways.
The significant PDSs originate from 58 different "involved" pathways.
The predominant impact of RDX involved pathways underlying "metabolism".
OCIAD2 is an immunoreactive antigen, which functions, involved pathways, and molecular mechanisms have never been reported.
The latest GO terms and involved pathways were collected from gene ontology consortium and KEGG database [ 33, 34].
Drugs are used to treat diseases by interacting with the sequential proteins through possible targets and involved pathways.
This result demonstrated for the first time that oncogenesis of the putative stem-cell-originated HCCs likely involved pathways independent of p53 mutations.
