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Both founders actually came from architectural backgrounds, and they could see the value of VDI in their previous field, but the large files and complex programs involved made it difficult to use VDI in that setting.
Client 01 felt that the level of involvement "impacts (my) willingness to seek treatment" both at the time and in the future, and his experiences of not being involved made it difficult for him to want to subsequently seek help or agree with decisions.
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Although the great number of functions in which this protein could be involved make it difficult to rule out a unique effect of the observed VCP increase in AQP4−/− muscle, the protein-protein interaction map seems to suggest a particular role of VCP over-expression in the up-modulation of protein-ubiquitination homeostasis.
Noise in the available microarray or annotation data as well as incomplete annotations can make the network reconstruction ambiguous, and the complexity of the underlying regulatory mechanism, in particular the combinatorics involved makes it difficult to draw direct inferences.
The complexity of the signaling pathways involved makes it difficult to experimentally test all possible interactions to determine which pathways in the signaling network are functional for a given condition.
He said that requiring officers to get permission before posting pictures involving department insignia made it difficult to share news about awards or honors spontaneously with family and friends.
As for why an exit to Google looked appealing to a company like Titan, Sarah Perez outlines how Titan had sparked early interest from VCs thanks to its massive drones, which were capable of flying at a reported altitude of 65,000 feet for up to three years, but how there was also a lot of risk involved that would've made it difficult to find sustained investment while remaining independent.
It started in a somewhat difficult environment involving some scepticism by existing services, which made it difficult initially to obtain referrals.
Ms Robb said the number of agencies involved - combined with the workload - also made it difficult for social workers to communicate effectively with other agencies.
Treatments exist for autism, but the cost of the intense, specialized teaching that is involved can make it difficult for even parents in the United States to obtain, let alone in a third-world country.
He said that initially the technology involved might make it difficult for some stations to place local commercials in the replayed ABC shows and that ABC has put a revenue-sharing arrangement in place to compensate the stations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com