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Clearly, a comparative analysis of antibody-induced internalization of Sn of other species and identification of internalization motifs involved, is needed to elucidate whether clathrin-dependent endocytosis is a general feature of Sn of different species, or whether this is a feature of pSn alone.
Information on mechanisms involved is needed to enhance surveillance and identify where LD risk is emerging.
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Further studies examining ecosystem dynamics within drainage ditches such as sediment and plant nutrient partitioning, as well as microbial processes involved, are needed to provide a better understanding of natural nutrient variability, seasonality and flux.
Additional evaluation of heart failure events and the potential mechanisms involved are needed to provide additional data on how best to manage patients with T2DM who are also at risk for heart failure.
We also describe possible molecular mechanisms of action of isoflavones; distinguishing which mechanism(s) are involved is needed if we are to solve the controversy surrounding the actions of these compounds.
Additional research involving longitudinal sampling is needed to understand the dynamics of bacterial communities in chronic wounds.
However, further research, involving larger sample sizes is needed to confirm these findings.
A necessarily interdisciplinary effort, involving both modelers and experimentalists, is needed to clear the path forward.
Additional longitudinal studies involving biomarkers are needed to further explore underlying mechanisms and susceptibilities.
Studies involving CT scans are needed to establish this.
Studies involving brain autopsies are needed to confirm that our findings are related to FTD pathology.
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CEO of Professional Science Editing for Scientists @ prosciediting.com