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In this section we explore how some topological features of the train of spreaders involved in a cascade affects its final size.
We infer ten surface proteins that are involved in a cascade of events in HIV infection.
In the usual description of the mechanisms of scaffolding, scaffold proteins are considered as reactors where molecules involved in a cascade of reactions are simultaneously bound with the right orientation to meet and interact.
Nonetheless, being a key member of the nucleosome-remodelling and –deacetylation (NuRD) complex, the androgen regulation of the MTA1 protein indicates that the MTA1 gene might be involved in a cascade of androgen-regulated events in the epididymis and especially attains considerable significance in the realm of epididymal sperm maturation.
This suggested that single copy genes may be involved in a cascade of processes in which single copy genes are first coded in nuclei, and then transported to organelles where single copy genes are very common.
Interestingly, both FOSL1 and C-JUN are part of the AP-1 transcription complex suggesting that this Alu-derived TFBS may be involved in a cascade of regulatory interactions.
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When a specific member of the Bone Morphogenetic Protein (BMP) family binds to endoglin, SMAD2 is involved in a signaling cascade: SMAD2 is driven to the nucleus, where it prevents cell proliferation, or cell growth, and thus prevents angiogenesis.
Furthermore, we do not know if these FIKK kinases target directly erythrocyte membrane proteins or are involved in a phosphorylation cascade.
Hh signaling activated genes that are potentially involved in a proteolytic cascade.
Posterior Hh signaling activates several genes potentially involved in a proteinase cascade of unknown function.
An intriguing feature of the Hh dataset is the large number of genes predicted to be involved in a proteolytic cascade, including a member of the spätzle family (Tc-spz1), which might act as a Toll ligand.
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