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The accused might appeal to the pope before proceedings began, but this involved considerable expense.
The public health response to this outbreak involved considerable expense.
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To do so sometimes involves considerable expense, danger, time, and inconvenience.
When a crane or dolly was used to shoot the live portion of the scene, the background had to be animated frame-by-frame, involving considerable expense in draftsmanship.
With respect to feasibility, numerous agents would have to be sampled many times in each area assessed, which would involve considerable expense.
Although there is no need to repeat all trials of the reference biopharmaceutical, the need to conduct some biosimilar trials enrolling several hundreds of patients involve considerable expense and time: a US study has estimated that the costs of biosimilar trials would range from US$10 to $40 million.
Domestic heating in winter involves considerable expenses, so the idea of energy conservation and the need to implement reliable and innovative solutions in the field of energy in constructions emerged.
No doubt the turnaround will require considerable expense and time.
The move, nevertheless, involved considerable risk.
Jamison's outing of her affliction involved considerable professional risk.
While highly effective, these methods are largely confined to laboratory settings, require trained personnel and can involve considerable time and expense.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com