Sentence examples for involved as a substrate from inspiring English sources
Since glutamate is a highly abundant metabolite and is involved as a substrate in 20 reactions in B. subtilis, it was not obvious which mutation could have lead to glutamate utilization proficiency in B. subtilis GP717.
The members of the TGF-β family bind to a heteromeric receptor complex on the cell surface and activate an intracellular signal transducing the Smad complex (a composite term derived from Sma genes from Caenorhabditis elegans and Mad gene (Drosophila melanogaster) involved as intracellular substrate for TGF-β and BMP signaling).
The latter pathway involves glycine as a substrate and produces GB via successive methylation of glycine by two different N-methyltransferase enzymes; glycine sarcosine methyltransferase (GSMT), and sarcosine dimethylglycine methyltransferase (SDMT).
RTP may also play an important role in the inhibition of VSV and SeV replication via interaction with viral polymerase (shown for RTP and VSV [18]), "error catastrophe" or any other mechanisms which involves RTP as a substrate for viral RNA polymerase.
However, TLR7-mediated regulation of lipoxygenases may not be the only mechanism involved as substrate availability is also critical.
Large polymeric molecules such as the acyl carrier protein (ACP) or tRNAs were included in the model when they were involved as substrate cofactors of biochemical reactions.
The compounds found in the metabolic networks are those which are involved as substrates or products in the inferred reactions.
A previous study showed that TIP60 co-localizes with the UHRF1/DNMT1 complex, which is involved in ubiquitination as a substrate of E3 ligase (Dai et al., 2013).
Number of neighbours indicates the number of enzyme-coding genes whose products catalyze reactions involving that metabolite either as a substrate or as a product.
In the preceding publications, atrial interstitial fibrosis was considered to be involved as the mechanism for constructing the arrhythmogenic substrate for AF because atrial fibrosis may destroy cell-to-cell electrophysiological coupling.
