Had the LUNAR trial aimed for a 12% efficacy difference and involved a 2-year duration, the study may have met its endpoint despite a small sample size.
For healthy subjects, Carr and Gentile [ 47] found that rising with the hands between the knees involved a significantly shorter duration of the maximum support moment (defined as the percentage of the extension phase during which the support moment equals or exceeds 3 times the body weight) compared with rising with the arms restricted.
The bribery, sweeping in scope and decades in duration, involved a $6 billion plan to bribe Nigerian officials to obtain engineering, procurement and construction contracts for a liquefied natural gas facility on Bonny Island in Nigeria.
40 Most of the trials in our study involved a reduced dose or duration of administration of rasburicase (Table 5).
However, this latter study, which included more subjects but involved a shorter follow-up duration, did find treatment effects for whole brain volume, ventricular enlargement and cortical grey matter volume.
We presented subjects (n = 5) with a central fixation cross and a movie of variable duration that involved a static or a moving figure, randomized on a trial-by-trial basis (Fig. 7).
Each trial involved a stimulus 5 10 s in duration, determined as min(10, 5 + τ), where τ was an exponentially distributed random variable, making trial terminations unpredictable within the given time frame.
Propecia's most recent FDA labeling reports three double-blind, randomized, placebo-controlled studies of 12-month duration, involving a total of 1879 men with mild to moderate (but not complete) hair loss.
Thyroidectomy, which is a clean incision, involves a small incision, short duration, and minor hemorrhage.
However, further studies of longer duration, involving a large number of patients, will be required to fully assess long-term cardiometabolic effects of taspoglutide.
118, 119 In a pooled analysis of seven randomized clinical trials of 5 13 weeks duration involving a total of 1510 patients, pregabalin at varying doses (150, 300, 600 mg) demonstrated a significant reduction in mean pain score.
