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Evolutionary habitat transitions often involve substantial modifications in morphology, physiology, and behaviour, particularly if the new habitat imposes novel physical challenges.
But they also both involve substantial uncertainty related to timing and severity.
They also involve substantial government spending.
Historical narratives have a substantial interpretive component, and involve substantial construction of the past.
Many cellular processes involve substantial shape changes.
More common "natural experiments" involve substantial changes in traffic patterns.
This area of work in Darwinian medicine involves substantial, one might even say onerous, challenges.
It took months of negotiation, involving "substantial persuasion" to agree "substantial changes".
The European fundamentalist wars between Protestants and Catholics, which involved substantial terror, crossed all economic boundaries.
Excess inventory involves substantial working capital.
"The defendant's covert influence campaign involved substantial planning, international coordination and preparation," prosecutors wrote.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com